[SCA1, SCA2, MJD/SCA3 (CAG)n mutation detection and analysis in patients with hereditary spinocerebellar ataxia from Chinese families].

Article

[SCA1, SCA2, MJD/SCA3 (CAG)n mutation detection and analysis in patients with hereditary spinocerebellar ataxia from Chinese families].

Zhonghua yi xue za zhi - 1 Nov 1997

Tang B, Wang D, Xia J

Abstract excerpt

OBJECTIVE: To assess the frequency of the SCA1, SCA2, MJD/SCA3 CAG trinucleotide repeat expansions ((CAG)n) among individuals diagnosed with hereditary spinocerebellar ataxia (SCA) from Chinese families. METHOD: The SCA1, SCA2, MJD/SCA3 (CAG)n mutation were detected with the polymerose chain reac...

Topics

Adolescent
Adult
Aged
Ataxin-1
Ataxin-3
Ataxins
China
Family Health
Female
Gene Frequency
Humans
Male
Middle Aged
Mutation
Nerve Tissue Proteins
Nuclear Proteins
Proteins
Repressor Proteins

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