Article
Clinical and laboratory findings in referrals for mitochondrial DNA analysis.
Archives of disease in childhood - 1 Jul 1998
Lamont P J, Surtees R, Woodward C E, Leonard J V, Wood N W, Harding A E
Abstract excerpt
BACKGROUND: Increasingly, mutations of mitochondrial DNA (mtDNA) are being considered when investigating the aetiology of neurological diseases in childhood. However, they are often difficult to predict clinically. METHOD: Mitochondrial DNA analysis was carried out on 190 children from 1992 to 19...
Topics
- Acidosis, Lactic
- Adolescent
- Age of Onset
- Cerebrovascular Disorders
- Child
- Child, Preschool
- DNA Mutational Analysis
- DNA, Mitochondrial
- Female
- Gene Rearrangement
- Genotype
- Humans
- Infant
- Kearns-Sayre Syndrome
- Leigh Disease
- Leukocytes
- Male
- Mitochondria, Muscle