Article
Molecular genetics of peroxidase deficiency.
Journal of molecular medicine (Berlin, Germany) - 1 Sept 1998
Petrides P E
Abstract excerpt
Myeloperoxidase (MPO) belongs to a family of related proteins which also includes eosinophil, thyroid, and lactoperoxidase. The MPO gene is a 14-kb gene located on the long arm of chromosome 17. Thus far four mutations (R569W, Y173C, M251T and a 14-base deletion in exon 9) have been identified in...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA Mutational Analysis
- Female
- Genotype
- Humans
- Male
- Metabolism, Inborn Errors
- Molecular Sequence Data
- Multigene Family
- Peroxidase
- Phenotype