Article
Use of the C3H/He Lyme disease mouse model for the recovery of a Spanish isolate of Borrelia garinii from erythema migrans lesions.
Research in microbiology - 1 Jan 1998
Oteo J A, Backenson P B, del Mar Vitutia M, García Moncó J C, Rodríguez I, Escudero R, Anda P
Abstract excerpt
A skin biopsy from a patient with erythema migrans was inoculated into C3H/He mice and into culture medium. A Borrelia garinii strain named Rio1 was isolated from both a direct BSK medium culture and a mouse ear-punch biopsy culture. Inoculating human tissue into mice produced a disease resulting...
Topics
- Animals
- Arthritis
- Bacteriological Techniques
- Borrelia
- Borrelia burgdorferi Group
- Child
- Disease Models, Animal
- Erythema Chronicum Migrans
- Genes, rRNA
- Genotype
- Humans
- Male
- Mice
- Mice, Inbred C3H
- Molecular Sequence Data
- Phenotype
- RNA, Ribosomal, 16S
- Spain