Article
[Combined hemostatic defects in family members of symptomatic carriers of Leiden mutations of factor V].
Polskie Archiwum Medycyny Wewnetrznej - 1 Mar 1998
Lewandowski K, Rozek M, Turowiecka Z, Markiewicz W T, Zawilska K
Abstract excerpt
The aim of the study was to determine the frequency of additional prothrombotic defect in family members of 14 symptomatic, heterozygous carriers of factor V Leiden mutation (FV Leiden). The FV Leiden was found in fifty-five from among 127 persons (43%). Thirty-two from 53 (68%) family carriers of FV Leiden had venous thromboembolic disease at the time of examination. Combined defects were found in 6 out of 14...
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