A splicing mutation of the RHAG gene associated with the Rhnull phenotype.

doi:10.1046/j.1469-1809.1998.6220107.x

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Article

A splicing mutation of the RHAG gene associated with the Rhnull phenotype.

Annals of human genetics - 1 Mar 1998

Kawano M, Iwamoto S, Okuda H, Fukuda S, Hasegawa N, Kajii E

Abstract excerpt

Rhnull is a syndrome serologically characterized by the deficiency of all Rh antigens on human red blood cells. Rhnull is divided into two types: regulator and amorph. Recently, Cherif-Zahar et al. proposed that the RHAG gene encoding the Rh50 glycoprotein is a candidate for inducing regulator ty...

Topics

Adolescent
Amino Acid Sequence
Base Sequence
Blood Proteins
Blotting, Southern
DNA, Complementary
Humans
Male
Molecular Sequence Data
Mutation
RNA Splicing
Reticulocytes
Rh-Hr Blood-Group System
Sequence Analysis, DNA

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