Article
A splicing mutation of the RHAG gene associated with the Rhnull phenotype.
Annals of human genetics - 1 Mar 1998
Kawano M, Iwamoto S, Okuda H, Fukuda S, Hasegawa N, Kajii E
Abstract excerpt
Rhnull is a syndrome serologically characterized by the deficiency of all Rh antigens on human red blood cells. Rhnull is divided into two types: regulator and amorph. Recently, Cherif-Zahar et al. proposed that the RHAG gene encoding the Rh50 glycoprotein is a candidate for inducing regulator type Rhnull. We investigated both the RH and RHAG genes in an Rhnull individual. The reticulocytes from the propositus...
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