Article
Role of multiple trans-acting regulators in modifying the effect of the retrotransposon copia on host gene expression in Drosophila.
Molecular & general genetics : MGG - 1 Aug 1998
Pal Bhadra M, Bhadra U, Birchler J A
Abstract excerpt
We have examined the combinatorial effect of five trans-acting modifiers of white apricot, a copia retrotransposon-induced allele of the white eye-color gene. Quantitation of steady-state levels of copia transcripts for various modifier combinations at different developmental stages using northern analysis reveals nonadditivity and epistasis. Interestingly, extensive overexpression of copia transcripts caused by...
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