Article
Familial hyperaldosteronism type II: description of a large kindred and exclusion of the aldosterone synthase (CYP11B2) gene.
The Journal of clinical endocrinology and metabolism - 1 Sept 1998
Torpy D J, Gordon R D, Lin J P, Huggard P R, Taymans S E, Stowasser M, Chrousos G P, Stratakis C A
Abstract excerpt
Familial hyperaldosteronism type II (FH-II) is characterized by autosomal dominant inheritance and hypersecretion of aldosterone due to adrenocortical hyperplasia or an aldosterone-producing adenoma; unlike FH type I (FH-I), hyperaldosteronism in FH-II is not suppressible by dexamethasone. Of a total of 17 FH-II families with 44 affected members, we studied a large kindred with 7 affected members that was...
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