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Article

Dominant optic atrophy: exclusion and fine genetic mapping of the candidate gene, HRY.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 1998

Votruba M, Payne A, Moore A T, Bhattacharya S S

Abstract excerpt

Autosomal dominant optic atrophy (OPA1) maps to Chromosome (Chr) 3q28, and the disease interval has been refined to within 1.4 cM, flanked by the markers D3S3669 and D3S3562. HRY, the human homolog of the Drosophila segmentation gene, hairy, maps by in situ hybridization to the chromosomal region 3q28-q29. We screened for mutations in HRY in 36 patients from 18 pedigrees with dominant optic atrophy and a group of...

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Identifiers

PMID: 9745030
DOI: 10.1007/s003359900867

Genes

OPA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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