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Article

Novel mutation of the PTEN gene in an Italian Cowden's disease kindred.

International journal of oncology - 1 Oct 1998

Scala S, Bruni P, Lo Muzio L, Mignogna M, Viglietto G, Fusco A

Abstract excerpt

Cowden disease (CD) is an autosomal dominant multiple hamartoma syndrome with an elevated risk of thyroid and breast cancers. The CD susceptibility gene has recently been identified as the PTEN/MMAC1/TEP1 gene localized at 10q23 and coding for a dual specificity protein phosphatase. We report the mutational analysis of the PTEN gene in one Italian CD kindred. By using the single strand conformation polymorphism...

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Source

Identifiers

PMID: 9735393
DOI: 10.3892/ijo.13.4.665

Genes

PTEN
TAT
TEP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel mutation of the PTEN gene in an Italian Cowden's disease kindred.PMID 9735393Read ↗

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