Article
Characterization of canine photoreceptor phosducin cDNA and identification of a sequence variant in dogs with photoreceptor dysplasia.
Gene - 30 Jul 1998
Zhang Q, Acland G M, Parshall C J, Haskell J, Ray K, Aguirre G D
Abstract excerpt
Photoreceptor dysplasia (pd) is an autosomal recessive disease of miniature schnauzer dogs causing retinal degeneration. The disease is a homologue of retinitis pigmentosa, a group of genetically heterogeneous diseases, causing blindness in humans. A subtraction library was prepared from retinas...
Topics
- Amino Acid Sequence
- Animals
- DNA Primers
- DNA, Complementary
- Dog Diseases
- Dogs
- Eye Proteins
- GTP-Binding Protein Regulators
- Genes, Recessive
- Genetic Carrier Screening
- Genetic Variation
- Molecular Sequence Data
- Phosphoproteins
- Photoreceptor Cells
- Polymerase Chain Reaction
- Restriction Mapping
- Retina
- Retinal Degeneration