Article
Newly described form of X-linked arthrogryposis maps to the long arm of the human X chromosome.
American journal of medical genetics - 6 Aug 1998
Zori R T, Gardner J L, Zhang J, Mullan M J, Shah R, Osborn A R, Houlden H, Wallace M R, Roberts S, Yang T P
Abstract excerpt
Arthrogryposis is a heterogeneous birth defect characterized by limitation of movement at multiple joints. One in 3,000 infants is born with arthrogryposis, and at least a third of these cases have a genetic cause. Four distinct types of X-linked arthrogryposis have been reported, and a severe le...
Topics
- Alleles
- Ankle Joint
- Arthrogryposis
- Chromosome Mapping
- Female
- Gait
- Gene Frequency
- Genetic Linkage
- Genotype
- Hip Joint
- Humans
- Knee Joint
- Lod Score
- Male
- Microsatellite Repeats
- Pedigree
- Phenotype
- Polymorphism, Restriction Fragment Length