Article
Relative contribution of low-density lipoprotein receptor and lipoprotein lipase gene mutations to angiographically assessed coronary artery disease among French Canadians.
The American journal of cardiology - 1 Aug 1998
Gaudet D, Vohl M C, Julien P, Tremblay G, Perron P, Gagné C, Bergeron J, Moorjani S, Després J P
Abstract excerpt
Men with low-density lipoprotein receptor gene mutations causing familial hypercholesterolemia (FH) are at high risk of premature coronary artery disease (CAD). The dyslipidemic state found among patients who are heterozygous for mutations in the lipoprotein lipase (LPL) gene may also increase th...
Topics
- Alleles
- Coronary Angiography
- Coronary Disease
- Gene Frequency
- Genotype
- Humans
- Hyperlipoproteinemia Type II
- Immunoelectrophoresis
- Lipoprotein Lipase
- Male
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- Quebec