Article
Human papillomavirus genotype as a major determinant of the course of cervical cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Aug 1998
Lombard I, Vincent-Salomon A, Validire P, Zafrani B, de la Rochefordière A, Clough K, Favre M, Pouillart P, Sastre-Garau X
Abstract excerpt
PURPOSE: To determine whether the prognosis of invasive cancers of the uterine cervix is related to the type of human papillomavirus (HPV) associated with the tumor. PATIENTS AND METHODS: Two hundred ninety-seven patients with invasive cervical cancer were prospectively registered from 1986 to 1994. HPV typing was performed on DNA extracted from frozen tumor specimens by means of Southern blot hybridization (SBH)...
Topics
- Adult
- Aged
- Blotting, Southern
- Carcinoma
- DNA, Viral
- Disease-Free Survival
- Female
- Genotype
- Humans
- Middle Aged
- Papillomaviridae
