Genotyping of hepatitis B virus by restriction pattern analysis of a pre-S amplicon.

doi:10.1016/s0166-0934(98)00026-3

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Article

Genotyping of hepatitis B virus by restriction pattern analysis of a pre-S amplicon.

Journal of virological methods - 1 Jun 1998

Lindh M, Gonzalez J E, Norkrans G, Horal P

Abstract excerpt

A method is described for genotyping of hepatitis B virus (HBV), based on the restriction fragment length polymorphism (RFLP) created by Ava2 and Dpn2 action on an amplified segment of the pre-S region. Analysing 51 database sequences by phylogenetic tree construction and RFLP prediction, the met...

Topics

Genotype
Hepatitis B virus
Humans
Phylogeny
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Virology

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