Article
Exclusion of identified LGMD1 loci from four dominant limb-girdle muscular dystrophy families.
Human heredity - 1 Jan 2000
Speer M C, Vance J M, Lennon-Graham F, Stajich J M, Viles K D, Gilchrist J M, Nigro V, McMichael R, Chutkow J G, Bartoloni L, Horrigan S K, Westbrook C A, Pericak-Vance M A
Abstract excerpt
The limb-girdle muscular dystrophies are a clinically and genetically heterogeneous group of disorders. Recent linkage analyses and positional cloning studies have identified numerous loci responsible for the recessive and dominant forms, underscoring the inherent heterogeneity. In this report, we investigate four large autosomal dominant limb-girdle pedigrees and exclude these pedigrees from linkage to these...
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