Analysis of a familial three way translocation involving chromosomes 3q, 6q, and 15q by high resolution banding and fluorescent in situ hybridisation (FISH) shows two different unbalanced karyotypes in sibs.

doi:10.1136/jmg.35.7.545

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Article

Analysis of a familial three way translocation involving chromosomes 3q, 6q, and 15q by high resolution banding and fluorescent in situ hybridisation (FISH) shows two different unbalanced karyotypes in sibs.

Journal of medical genetics - 1 Jul 1998

Wieczorek D, Engels H, Viersbach R, Henke B, Schwanitz G, Passarge E

Abstract excerpt

We report on a familial three way translocation involving chromosomes 3, 6, and 15 identified by prometaphase banding and fluorescence in situ hybridisation (FISH). Two mentally retarded sibs with different phenotypic abnormalities, their phenotypically normal sister and mother, and two fetuses o...

Topics

Adult
Chromosome Banding
Chromosome Deletion
Chromosomes, Human, Pair 15
Chromosomes, Human, Pair 3
Chromosomes, Human, Pair 6
Female
Genetic Counseling
Humans
In Situ Hybridization, Fluorescence
Intellectual Disability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Karyotyping

Male

Pedigree

Phenotype

Pregnancy

Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 9678698
DOI: 10.1136/jmg.35.7.545
PMCID: PMC1051364

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9678698-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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