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Article

Genetics of Mycobacterium tuberculosis and genotyping of drug resistance.

Rays - 1 Jan 2000

Ortona L, Cingolani A

Abstract excerpt

During the last decade, molecular genetics has been applied to the study of mycobacteria, of Mycobacterium tuberculosis in particular. The identification of plasmids and phages able to transfer DNA cloned from Escherichia coli to M. tuberculosis has allowed to draw important information on immunogenic proteins, drug resistance, virulence and mechanisms of mycolic acid biosynthesis. Insertion sequences have been...

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PMID: 9673133

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