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Article

Human occult loiasis: field evaluation of a nested polymerase chain reaction assay for the detection of occult infection

1 Jun 1998

Abstract excerpt

A nested polymerase chain reaction (nested PCR) assay, targeted on the repeat 3 region (15r3) of the gene coding for a Loa loa 15 kD polyprotein, was developed to detect L. loa infection. The assay has a sensitivity of 95% and is 100% specific with regard to sympatric filarial parasites: Mansonella perstans, Onchocerca volvulus and Wuchereria bancrofti. In this field study in a mixed filarial (L. loa and M....

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PMID: 9657514
DOI: 10.1046/j.1365-3156.1998.00260.x

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