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Article

Borna Disease in a Dog with Lethal Meningoencephalitis

1 Jul 1998

Abstract excerpt

A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the...

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Identifiers

PMID: 9650982
DOI: 10.1128/jcm.36.7.2127-2130.1998

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