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The effects of antioxidant supplementation during Percoll preparation on human sperm DNA integrity

1 May 1998

Abstract excerpt

The integrity of sperm DNA is crucial for the maintenance of genetic health. A major source of damage is reactive oxygen species (ROS) generation; therefore, antioxidants may afford protection to sperm DNA. The objectives of the study were, first, to measure the effects of antioxidant supplementation in vitro on endogenous DNA damage in spermatozoa using the single cell gel electrophoresis (comet) assay and,...

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PMID: 9647554
DOI: 10.1093/humrep/13.5.1240

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