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Genetic organization and sequence analysis of the hypha-specific cell wall protein geneHWP1 ofCandida albicans

1 May 1998

Abstract excerpt

A previously isolated partial cDNA encoding a cell wall protein antigen found on hyphal surfaces of the opportunistic fungal pathogen, Candida albicans (Staab et al., 1996) was used to clone the complete hyphal wall protein 1 gene (HWP1). Hyphal forms of C. albicans invade mucosal surfaces of immunocompromised patients such as those with AIDS. HWP1 consisted of an open reading frame predicting an acidic protein...

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PMID: 9639315
DOI: 10.1002/(sici)1097-0061(199805)14:7<681::aid-yea256>3.0.co;2-8

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