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Article

Molecular cloning of sucrase-isomaltase cDNA in the house musk shrew Suncus murinus and identification of a mutation responsible for isolated sucrase deficiency.

The Journal of biological chemistry - 26 Jun 1998

Ito T, Hayashi Y, Ohmori S, Oda S, Seo H

Abstract excerpt

Isolated sucrase deficiency has been demonstrated in a line of house musk shrew, Suncus murinus (laboratory name: suncus). This animal belongs to the order Insectivore and is phylogenetically different from ordinarily used laboratory animals. They are believed to have evolved with mainly animal food without sucrose. To study the molecular basis of the sucrase deficiency in suncus, we cloned 6. 0-kilobase (kb)...

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PMID: 9632713
DOI: 10.1074/jbc.273.26.16464

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