Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Legg-Perthes disease in three siblings, two heterozygous and one homozygous for the factor V Leiden mutation.

The Journal of pediatrics - 1 May 1998

Gruppo R, Glueck C J, Wall E, Roy D, Wang P

Abstract excerpt

A family is described with three-generation transmission of factor V Leiden (a thrombophilic mutation that causes resistance to activated protein C). Legg-Perthes disease developed in three siblings in this family. The male proband and his sister were heterozygous for the mutation and had unilate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool
Share to Factor V

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterozygote

Share to Homozygote

Share to Mutation

Share to Pedigree

Share to Protein C

Source

Identifiers

PMID: 9602208
DOI: 10.1016/s0022-3476(98)70326-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9602208-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Legg-Perthes disease in three siblings, two heterozygous and one homozygous for the factor V Leiden mutation.PMID 9602208Read ↗

Legg-Calve-Perthes disease, venous and arterial thrombi, and the factor V Leiden mutation in a four-generation kindred.Semantic proximity Read ↗

Resistance to activated protein C and Legg-Perthes disease.Semantic proximity Read ↗

Legg-Calve-Perthes disease in two generations of male family members: a case report.Semantic proximity Read ↗

Legg-perthes disease and heritable thrombophilia.Semantic proximity Read ↗

The beta fibrinogen gene G-455-A polymorphism is a risk factor for Legg-Perthes disease.Semantic proximity Read ↗

Homozygous factor V Leiden mutation in two siblings presenting with acute myocardial infarction: a rare cause of myocardial infarction in the young.Semantic proximity Read ↗

Recurrence of achondrogenesis type II within the same family: evidence for germline mosaicism.Semantic proximity Read ↗

Prospective reevaluation of the association between thrombotic diathesis and legg-perthes disease.Semantic proximity Read ↗

Recurrent ulcerations on both legs since early childhood due to a factor V gene mutation.Semantic proximity Read ↗

Recurrent Legg-Calvé-Perthes disease: case report and long-term followup.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.