Article
Molecular background of the Finnish disease heritage.
Annals of medicine - 1 Dec 1997
Peltonen L
Abstract excerpt
Finland has a population with a history revealing features of founder effect, genetic drift and isolation. Relatively small founder populations have slowly inhabited a large country and internal isolates have developed within Finland. This is reflected even today in the regional enrichment of som...
Topics
- Aspartylglucosaminuria
- Aspartylglucosylaminase
- Biology
- Chromosome Mapping
- DNA
- Finland
- Founder Effect
- Gene Frequency
- Gene Pool
- Genetic Diseases, Inborn
- Humans
- Metabolism, Inborn Errors
- Molecular Biology
- Neuronal Ceroid-Lipofuscinoses
- Phenotype
- Point Mutation
- Proteins
- Structure-Activity Relationship