Article
Mitochondrial deafness.
Annals of medicine - 1 Dec 1997
Jacobs H T
Abstract excerpt
Hearing impairment is a common disorder, largely genetic in origin, and showing classical features of a heterogeneous genetic disease. Up to 100 independently acting nuclear genes are involved in the disorder, of which around 30 have been mapped, but only a handful identified. Mutations in mitoch...
Topics
- Adenosine Triphosphatases
- Aminoglycosides
- Anti-Bacterial Agents
- Chromosome Mapping
- DNA, Mitochondrial
- Deafness
- Environmental Exposure
- Fungal Proteins
- Gene Expression
- Genes
- Hearing Loss, Sensorineural
- Humans
- Membrane Proteins
- Mitochondria
- Mutation
- Phenotype
- Protein Biosynthesis
- Proteins