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Article

Nuclear and cytoplasmic determinants involved in the regulation of mammalian oocyte maturation

1 Jan 1998

Abstract excerpt

The requisite endpoint of mammalian oocyte maturation, whether in vivo or in vitro, is a metaphase II oocyte which is able to be fertilized and which can eventually support normal embryonic development. Oocytes which have been matured in vivo basically fulfill these criteria. On the other hand, a completely different situation exists when these cells are isolated from the ovaries and cultured in vitro. If they...

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PMID: 9510010
DOI: 10.1093/molehr/4.1.41

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