Article
The evaluation of factor VIII binding activity of von Willebrand factor by means of an ELISA method: significance and practical implications.
American journal of clinical pathology - 1 Mar 1998
Casonato A, Pontara E, Zerbinati P, Zucchetto A, Girolami A
Abstract excerpt
One of the functions of von Willebrand factor (vWF) is to serve as a carrier of clotting factor VIII (FVIII). Deficiency of this function results in the von Willebrand disease (vWD) variant type 2N, which resembles hemophilia A. We describe a new sandwich enzyme-linked immunosorbent assay (ELISA)...
Topics
- Adult
- Aged
- Enzyme-Linked Immunosorbent Assay
- Factor VIII
- Female
- Humans
- Male
- Middle Aged
- Mutation
- Recombinant Proteins
- Sensitivity and Specificity
- von Willebrand Diseases
- von Willebrand Factor