Article
BSE: can we predict the future?
Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie - 1 Jan 1997
Plum J
Abstract excerpt
Prion diseases are transmissible neurodegenerative disorders of humans and animals. The prion protein (PrPc) gene is expressed to some extent in many cell types but principally in neurons. Normal PrPc may contribute in the protection of neurons and are protease sensitive. Abnormal prions consist of a post-translationally modified form of PrP, PrPsc, which is partly protease resistant. PrPsc is a protein with high...
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