Article
Alpha1-antitrypsin alleles and phenotypes in patients with inflammatory bowel disease.
Scandinavian journal of gastroenterology - 1 Jan 1998
Folwaczny C, Urban S, Schröder M, Hofmann B, Noehl N, König A, Loeschke K, Fricke H
Abstract excerpt
BACKGROUND: Several studies suggest an imbalance of protease activation and inhibition in inflammatory bowel disease. Alpha1-Antitrypsin (AAT), one protease inhibitor of paramount importance, exists in numerous subtypes, some of them representing deficient phenotypes. The present study evaluated the prevalence of AAT-alleles and phenotypes in patients with inflammatory bowel disease. METHODS: The study population...
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