Article
Origin and mechanism of formation of 45,X/47,XX,+21 mosaicism in a fetus.
American journal of medical genetics - 3 Feb 1998
Harada N, Abe K, Nishimura T, Sasaki K, Ishikawa M, Fujimoto M, Matsumoto T, Niikawa N
Abstract excerpt
Chromosome analysis of amniotic fluid cells from a 17-week-old fetus with a nuchal cystic hygroma showed a 45,X/47,XX,+21 karyotype. Analyses of cord blood lymphocytes, skin fibroblasts, amniotic membrane, and chorionic villi demonstrated both cell lines in various proportions. We studied the ori...
Topics
- Alleles
- Amniocentesis
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 21
- Down Syndrome
- Fetus
- Fibroblasts
- Genetic Markers
- Genotype
- Humans
- Karyotyping
- Mosaicism
- Phenotype
- Ploidies
- Trisomy
- Turner Syndrome
- X Chromosome