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Article

Pattern of inheritance in hereditary myeloperoxidase deficiency associated with the R569W missense mutation.

Journal of leukocyte biology - 1 Feb 1998

Nauseef W M, Cogley M, Bock S, Petrides P E

Abstract excerpt

Myeloperoxidase (MPO) is an essential component of the oxygen-dependent microbicidal system of neutrophils and monocytes. Hereditary deficiency of MPO occurs in 1 in 2,000 to 4,000 individuals in the general population and has been generally considered an autosomal recessive trait. Previous studies have used the peroxidase activity of blood leukocytes to assess the phenotype of affected family members. Eosinophil...

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Source

Identifiers

PMID: 9468285
DOI: 10.1002/jlb.63.2.264

Genes

MPO
EPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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