Peroxisomal disorders: genotype, phenotype, major neuropathologic lesions, and pathogenesis.

doi:10.1111/j.1750-3639.1998.tb00139.x

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Article

Peroxisomal disorders: genotype, phenotype, major neuropathologic lesions, and pathogenesis.

Brain pathology (Zurich, Switzerland) - 1 Jan 1998

Powers J M, Moser H W

Abstract excerpt

Neurological dysfunction is a prominent feature of most peroxisomal disorders. Enormous progress in defining their gene defects has been achieved. The genes and gene products, peroxins (PEX), in five of the complementation groups have been defined. These studies confirm that Zellweger syndrome (Z...

Topics

Adrenoleukodystrophy
Animals
Genotype
Humans
Nerve Degeneration
Nervous System Diseases
Peroxisomal Disorders
Phenotype
Zellweger Syndrome

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