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Expression of glucose transporter and glucose uptake in human oocytes and preimplantation embryos

1 Nov 1997

Abstract excerpt

The expression of glucose transporters 1, 2, 3 and 4 was evaluated in human oocytes and polyploid preimplantation embryos. Only glucose transporter 1 (GLUT-1) isoform was detected in oocytes and in 2-12-cell stage embryos. Glucose uptake was markedly increased in embryos as compared to oocytes (19.7 +/- 3.4 pmol/min/embryo and 2.3 +/- 0.3 pmol/min/oocyte), and GLUT-1 was inhibited by cytochalasin B. These results...

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PMID: 9436695
DOI: 10.1093/humrep/12.11.2508

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