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Article

Epidemiology of cagA/vacA genes in H. pylori isolated from children and adults in Poland.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society - 1 Sept 1997

Gzyl A, Berg D E, Dzierzanowska D

Abstract excerpt

Serious lesions in gastric mucosa seem to be a result of infection with more pathogenic H. pylori strains. It was shown that two different proteins: CagA and VacA are the pathogenicity markers of H. pylori. CagA/VacA profile is associated with high intensity of inflammation and development of peptic ulcer disease. Presence of CagA protein depends on possession by a strain of cagA gene. VacA protein is expressed...

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PMID: 9376616

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