Higher proportion of intact exon 9 CFTR mRNA in nasal epithelium compared with vas deferens.

doi:10.1093/hmg/6.12.2099

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Article

Higher proportion of intact exon 9 CFTR mRNA in nasal epithelium compared with vas deferens.

Human molecular genetics - 1 Nov 1997

Mak V, Jarvi K A, Zielenski J, Durie P, Tsui L C

Abstract excerpt

The 5-thymidine (5T) variant of the cystic fibrosis transmembrane conductance regulator (CFTR) intron 8 polypyrimidine tract (IVS8-T tract) is the most frequent CFTR gene alteration identified in men with congenital bilateral absence of vas deferens (CBAVD). This alternative splicing variant give...

Topics

Alleles
Cystic Fibrosis Transmembrane Conductance Regulator
Epithelium
Exons
Genotype
Humans
Introns
Male
Nasal Mucosa
Poly T
Polymerase Chain Reaction
RNA, Messenger
Vas Deferens

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