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Article

Neurofibrillary tangles in Gerstmann-Sträussler-Scheinker syndrome with the A117V prion gene mutation.

Journal of neurology, neurosurgery, and psychiatry - 1 Aug 1997

Tranchant C, Sergeant N, Wattez A, Mohr M, Warter J M, Delacourte A

Abstract excerpt

One patient of a French family with Gerstmann-Sträussler-Scheinker syndrome with the mutation in codon 117 of the prion protein (PrP) gene displayed unexpected neuritic degeneration around PrP plaques and numerous diffuse neurofibrillary tangles, whereas other members did not. The tau profile in this patient's brain was analysed and compared with one from another member of the Gerstmann-Sträussler-Scheinker...

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Source

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Identifiers

PMID: 9285466
DOI: 10.1136/jnnp.63.2.240
PMCID: PMC2169673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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