Distinct spectrum of CFTR gene mutations in congenital absence of vas deferens.

doi:10.1007/s004390050518

Article

Distinct spectrum of CFTR gene mutations in congenital absence of vas deferens.

Human genetics - 1 Sept 1997

Dörk T, Dworniczak B, Aulehla-Scholz C, Wieczorek D, Böhm I, Mayerova A, Seydewitz H H, Nieschlag E, Meschede D, Horst J, Pander H J, Sperling H, Ratjen F, Passarge E, Schmidtke J, Stuhrmann M

Abstract excerpt

Congenital absence of the vas deferens (CAVD) is a frequent cause for obstructive azoospermia and accounts for 1%-2% of male infertility. A high incidence of mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene has recently been reported in males with CAVD. We have inv...

Topics

Adult
Cystic Fibrosis Transmembrane Conductance Regulator
DNA Mutational Analysis
Humans
Male
Mutation
Vas Deferens

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