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Article

Rapid DNA-based prenatal diagnosis by genetic linkage in three families with Alport's syndrome.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Aug 1997

Turco A E, Bresin E, Rossetti S, Peterlin B, Morandi R, Pignatti P F

Abstract excerpt

Alport's syndrome (AS) is a clinically and genetically heterogeneous progressive inherited glomerulonephritis characterized by hematuria, sensorineural hearing loss, ocular lesions, and specific alterations of the glomerular basement membrane. Typically, AS shows an X-linked dominant pattern of inheritance, with mutations affecting the collagen type IV alpha5 chain gene (COL4A5) at Xq22. Rarely, AS is caused in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9261027
DOI: 10.1016/s0272-6386(97)90050-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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