Article
Polymerase chain reaction screening for Y chromosome microdeletions: a first step towards the diagnosis of genetically-determined spermatogenic failure in men.
Molecular human reproduction - 1 Oct 1996
Qureshi S J, Ross A R, Ma K, Cooke H J, Intyre M A, Chandley A C, Hargreave T B
Abstract excerpt
Overall, approximately 11% of men attending infertility clinics suffer unexplained oligo- or azoospermia. Cytogenetic observations of loss of the distal portion of the Y chromosome long arm (Yq) were found to be associated with disrupted spermatogenesis. The existence of a gene locus involved in...
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