Article
Familial transmission of a deletion of chromosome 21 derived from a translocation between chromosome 21 and an inverted chromosome 22.
American journal of medical genetics - 27 Jun 1997
Aviv H, Lieber C, Yenamandra A, Desposito F
Abstract excerpt
Chromosome analysis of a newborn boy with Down syndrome resulted in the identification of a family with an unusual derivative chromosome 22. The child has 46 chromosomes, including two chromosomes 21, one normal chromosome 22, and a derivative chromosome 22. Giemsa banding and fluorescent in situ...
Topics
- Adult
- Chromosome Deletion
- Chromosome Inversion
- Chromosomes, Human, Pair 21
- Chromosomes, Human, Pair 22
- Down Syndrome
- Family Health
- Female
- Growth Disorders
- Humans
- Infant
- Infectious Disease Transmission, Vertical
- Male
- Pedigree
- Phenotype
- Translocation, Genetic