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Article

B-cell-negative severe combined immunodeficiency associated with a common gamma chain mutation.

Human genetics - 1 May 1997

Jones A M, Clark P A, Katz F, Genet S, McMahon C, Alterman L, Cant A, Kinnon C

Abstract excerpt

Severe combined immunodeficiency (SCID) is caused by a variety of underlying defects. Approximately 40% of cases are thought to be of the X-linked type (SCIDX1), which is phenotypically characterised by the absence, or very low numbers, of T cells, but normal or even high B cell numbers. The gene responsible for SCIDX1 is that coding for the common gamma chain (gamma c), a component of multiple cytokine...

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PMID: 9150740
DOI: 10.1007/s004390050428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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