Article
Polymorphic molecular markers from anonymous nuclear DNA for genetic analysis of populations.
Molecular ecology - 1 Apr 1997
Bagley M J, Medrano J F, Gall G A
Abstract excerpt
A simple method is presented for developing polymorphic, anonymous DNA markers suitable for population genetic studies. Anonymous DNA fragments are screened for sequence variability using a common mutation detection technique (single strand conformation polymorphism analysis; SSCP) and locus-specific PCR primers are designed for polymorphic DNA fragments. Detection of the markers by SSCP analysis coupled with...
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