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Article

An axenic amastigote system for drug screening

1 Apr 1997

Abstract excerpt

Currently available primary screens for selection of candidate antileishmanial compounds are not ideal. The choices include screens that are designed to closely reflect the situation in vivo but are labor-intensive and expensive (intracellular amastigotes and animal models) and screens that are designed to facilitate rapid testing of a large number of drugs but do not use the clinically relevant parasite stage...

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PMID: 9087496
DOI: 10.1128/aac.41.4.818

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