[Spinocerebellar ataxia: advances in genetic research and its clinical implication].

Article

[Spinocerebellar ataxia: advances in genetic research and its clinical implication].

[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 Jan 1997

Sasaki H

Abstract excerpt

Hereditary spinocerebellar ataxia (SCA) is a cluster of genetically heterogeneous disorders, and was classified based on the mode of inheritance and clinicopathological features. Recent molecular genetic studies determined the locus of responsible mutation in 7 dominant SCAs ¿SCA1, SCA2, Machado-...

Topics

Age of Onset
Chromosome Mapping
Genes, Dominant
Genes, Recessive
Genotype
Humans
Mutation
Phenotype
Spinocerebellar Degenerations
Trinucleotide Repeats

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