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Article

Bipolar localization of the replication origin regions of chromosomes in vegetative and sporulating cells of B. subtilis.

Cell - 7 Mar 1997

Webb C D, Teleman A, Gordon S, Straight A, Belmont A, Lin D C, Grossman A D, Wright A, Losick R

Abstract excerpt

To investigate chromosome segregation in B. subtilis, we introduced tandem copies of the lactose operon operator into the chromosome near the replication origin or terminus. We then visualized the position of the operator cassettes with green fluorescent protein fused to the Lac1 repressor. In sporulating bacteria, which undergo asymmetric cell division, origins localized near each pole of the cell whereas...

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Identifiers

PMID: 9054506
DOI: 10.1016/s0092-8674(00)81909-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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