Cardiovascular malformations in Smith-Lemli-Opitz syndrome.

Article

Cardiovascular malformations in Smith-Lemli-Opitz syndrome.

American journal of medical genetics - 31 Jan 1997

Lin A E, Ardinger H H, Ardinger R H, Cunniff C, Kelley R I

Abstract excerpt

We reviewed 215 patients (59 new, 156 from the literature) with Smith-Lemli-Opitz syndrome (SLOS), and found that 95 (44%) had a cardiovascular malformation (CVM). Classifying CVMs by disordered embryonic mechanisms, there were 5 (5.3%) class 1 (ectomesenchymal tissue migration abnormalities), 56...

Topics

Female
Heart Defects, Congenital
Humans
Male
Phenotype
Smith-Lemli-Opitz Syndrome

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