Periodic vestibulocerebellar ataxia, an autosomal dominant ataxia with defective smooth pursuit, is genetically distinct from other autosomal dominant ataxias.

doi:10.1001/archneur.1996.00550040074016

Article

Periodic vestibulocerebellar ataxia, an autosomal dominant ataxia with defective smooth pursuit, is genetically distinct from other autosomal dominant ataxias.

Archives of neurology - 1 Apr 1996

Damji K F, Allingham R R, Pollock S C, Small K, Lewis K E, Stajich J M, Yamaoka L H, Vance J M, Pericak-Vance M A

Abstract excerpt

BACKGROUND: Periodic vestibulocerebellar ataxia is an autosomal dominant disorder characterized by defective smooth pursuit, gaze-evoked nystagmus, ataxia, and vertigo. The age of onset ranges from the third to the sixth decade. To date, all patients have originated from North Carolina, suggestin...

Topics

Alleles
Ataxia
Cerebellar Ataxia
Genes, Dominant
Humans
Male
Middle Aged
Pedigree
Periodicity
Pursuit, Smooth
Vestibular Nuclei

Periodic vestibulocerebellar ataxia, an autosomal dominant ataxia with defective smooth pursuit, is genetically distinct from other autosomal dominant ataxias.

Abstract excerpt

Topics

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