Article
Analysis of the DRPLA triplet repeat in brain tissue and leukocytes from schizophrenics.
Psychiatric genetics - 1 Jan 1996
Brando L J, Yolken R, Herman M M, Kleinman J E, Ross C A, Torrey E F
Abstract excerpt
An expansion of the CAG triplet in the human gene called atrophin-1 or CTG-B37 causes the neuropsychiatric disease known as dentatorubral-pallidoluysian atrophy (DRPLA). We have examined the genomic DNA from brains and peripheral blood leukocytes (PBLs) of schizophrenic and non-schizophrenic individuals and PBLs from a cohort of monozygotic twins discordant or concordant for schizophrenia, for expansions of the...
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