Analysis of the DRPLA triplet repeat in brain tissue and leukocytes from schizophrenics.

doi:10.1097/00041444-199621000-00001

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Article

Analysis of the DRPLA triplet repeat in brain tissue and leukocytes from schizophrenics.

Psychiatric genetics - 1 Jan 1996

Brando L J, Yolken R, Herman M M, Kleinman J E, Ross C A, Torrey E F

Abstract excerpt

An expansion of the CAG triplet in the human gene called atrophin-1 or CTG-B37 causes the neuropsychiatric disease known as dentatorubral-pallidoluysian atrophy (DRPLA). We have examined the genomic DNA from brains and peripheral blood leukocytes (PBLs) of schizophrenic and non-schizophrenic indi...

Topics

Alleles
Brain Chemistry
Cohort Studies
Diseases in Twins
Genes
Humans
Leukocytes
Nerve Tissue Proteins
Polymerase Chain Reaction
Schizophrenia
Trinucleotide Repeats
Twins, Monozygotic

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