Article
Influence of vitamin D receptor genotype on bone mass changes after renal transplantation.
Kidney international - 1 Nov 1996
Torres A, Machado M, Concepción M T, Martín N, Lorenzo V, Hernández D, Rodríguez A P, Rodríguez A, de Bonis E, González-Posada J M, Hernández A, Salido E
Abstract excerpt
Renal transplant patients immunosuppressed with cyclosporine A (CsA) exhibit both a significant bone loss and an increased rate of bone fractures. An association between common allelic variants of the the vitamin D receptor (VDR) gene and bone mineral density and turnover has been reported in adults. However, the genetic influence on the rate of bone loss after renal transplantation has not been explored. We...
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